Is Calcium Formate Toxic?
Jan 06, 2024
Introduction
Calcium formate is a chemical compound that is commonly used in various industries such as construction, animal feed, and food. It is known for its excellent properties such as water solubility, heat resistance, and corrosion inhibition. Despite its widespread use, concerns about the toxicity of calcium formate have been raised. In this article, we will explore the safety of calcium formate and whether it is toxic.
What is Calcium Formate?
Calcium formate is a white crystalline substance with a chemical formula of Ca(HCOO)2. It is the calcium salt of formic acid and is also known as calcium diformate. It is a hygroscopic solid that readily dissolves in water and is used in a wide range of applications. Calcium formate is commonly used as an additive in animal feed, as a corrosion inhibitor in the construction industry, and as a preservative in the food industry.
Uses of Calcium Formate
Calcium formate is widely used in the construction industry as a corrosion inhibitor and as a concrete additive. Its properties of water solubility, heat resistance, and corrosion inhibition make it suitable for use in harsh environments. It is used in the production of cement, concrete, and mortar to improve their strength and durability.
Calcium formate is also used in the animal feed industry as a feed additive. It is used to prevent the growth of mold and bacteria in animal feed and to promote the growth of beneficial bacteria in the gut of animals. It has been shown to improve the health and growth of chickens, pigs, and other animals.
In the food industry, calcium formate is used as a preservative and antioxidant. Its ability to inhibit the growth of bacteria and mold makes it a valuable addition to many foods such as bread, cheese, and meat products.
Is Calcium Formate Toxic?
The toxicity of calcium formate has been a topic of discussion for many years. Some studies have suggested that calcium formate may have toxic effects on humans and animals. However, there is no clear evidence that suggests that calcium formate is toxic at normal exposure levels.
Studies have shown that calcium formate is relatively non-toxic to humans and animals. In fact, it is classified as a GRAS (Generally Recognized As Safe) substance by the FDA. The LD50 (Lethal Dose 50) of calcium formate has been estimated to be between 3,500 - 4,000 mg/kg in rats. This means that a rat would have to ingest a large amount of calcium formate before it would be toxic.
Possible Side Effects of Calcium Formate
Although calcium formate is considered relatively non-toxic, there have been reports of side effects associated with its use. Some people have reported allergic reactions such as skin rashes, hives, and itching after exposure to calcium formate. In rare cases, exposure to calcium formate has been reported to cause asthma-like symptoms and respiratory irritation.
In animal studies, exposure to high levels of calcium formate has been shown to cause liver damage and kidney damage. However, these effects were only observed at very high levels and are unlikely to occur in normal exposure scenarios.
Conclusion
In conclusion, calcium formate is a relatively safe chemical compound that is widely used in various industries. It is non-toxic at normal exposure levels and has been classified as a GRAS substance by the FDA. Although there are reports of side effects associated with its use, these are generally rare and occur at very high exposure levels.
If you are concerned about the use of calcium formate in any products you consume or use, it is always best to consult with a medical professional or toxicologist. They can provide you with more information about the safety of calcium formate and help you make informed decisions about its use.


